The Village of Burr Ridge is home to over 400 businesses. The following is a list of major businesses located in Burr Ridge:
| EMPLOYER | PRODUCT/SERVICE | EMPLOYEES |
| Case Corporation | Agricultural Equipment Research | 580 |
| M & M/Mars | Manufacturer of Frozen Novelties | 350 |
| McGraw-Hill Companies | Publishing Corporate Office | 350 |
| TCF National Bank | Banking Corporate Office | 335 |
| American Marketing Systems | Direct Marketing | 220 |
| Life Time Fitness | Health & Fitness Club | 200 |
| Praxair | Gases/Cryogenics for Food Industry | 180 |
| King Bruwaert House | Retirement Community | 150 |
| Codilis & Associates, Inc. | Law firm | 140 |
| BankFinancial, F.S.B. | Financial services administration | 140 |
| Bronson & Bratton, Inc. | Mfr. of Tungsten & Ceramic Dies & Tools | 130 |
| Fine Arts Engraving | Engraved Stationery Products | 130 |
| Timemed Labeling Systems | Label Converters for Healthcare Industry | 120 |
| Hansen Technologies | Industrial Refrigeration Equipment | 120 |
| Meaden Screw Products | Metal Fabricating | 114 |
| Goldstine, Skrodzki, Russian, Nemec & Hoff Ltd. | Law firm | 106 |
| Rockwell Automation | Regional Sales | 100 |
| Madison Ridge Associates | Multi-tenant Office Bldg Management | 100 |
| Central Decal Company | Pressure Sensitive Labels | 95 |
| Computershare Investor Service | Printing/Data Entry-Securities/Stocks | 95 |
| Dik Drug Company | Pharmaceutical Warehouse | 90 |
| Alliance Pharmacy Services | Long-term care pharmacy office/warehouse | 90 |
| Alliance, A Rock-Tenn Company | Mfg. permanent point of purchase displays | 85 |